Target Selectivity of Multispecific Antibodies: Practical Analysis of Binding Kinetics and Avidity
Bispecific antibodies are promising therapeutics for targeting cancer cells with high specificity.
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Insights Into Multi Fluorescence NTA Based EV Characterization – ISEV ‘EV Imaging in Vivo’ Workshop
Nanoparticle Tracking Analysis (NTA) with the Particle Metrix ZetaView® instrument family allows fast and reliable measurement of size, concentration, and Zeta Potential of nanoparticles. In contrast to scatter-based particle detection, fluorescence detection capability of the ZetaView® instrument allows the user to get biochemical information about particles. This increases the resolution and discriminatory power of the data. Furthermore,…
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The pH Value Is a Key Factor in Cell and Tissue Cultures
The term ‘pH’ is derived from either ‘pondus hydrogenii’ or ‘potentia hydrogenii.’ Both are originally Latin phrases, with ‘pondus hydrogenii’ meaning ‘weight of hydrogen’ and ‘potentia hydrogenii’ meaning ‘power of hydrogen.’ The pH value is a non-dimensional number that measures how acidic or alkaline an aqueous solution is. It is defined as the negative decimal logarithm of the concentration of hydrogen ions. The strength of the acid or alkali is identified by color indicators.
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Live Cell Imaging – An Overview for Beginners
Live cell imaging is a widely-used microscopy technique to study the behavior and the function of living cells in real time. It is indispensable for achieving a better understanding of the biological dynamics within cells, which cannot be properly analyzed using microscopy of fixed samples. Topics that can be addressed using live cell microscopy include the study of cell migration, the analysis of cell-cell-interaction, and the monitoring of molecule localization, among others.
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Moving from 2D to 3D – Advanced Tools from Ibidi
Cell culture assays with two-dimensional monolayers have been a well-established and convenient tool for investigating cell behavior and function in many areas of cell biology, such as cancer biology and stem cell research. However, these 2D assays come with certain limitations, since they do not accurately reflect the in vivo cell-to-cell interactions. Because of these limitations, 3D cell culture models have gained more and more relevance, as they have been proven to yield more accurate insights and data about cell function, structure, and morphology.
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How Can (Fluorescent) Live Cell Imaging Be Used for Cell Viability Analysis?
Alternative methods to traditional viability assays
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4 Ways To Reduce Non-specific Binding in Surface Plasmon Resonance Experiments
During an SPR experiment, there are many experimental parameters that must be controlled in order to optimize the performance of the system and to generate high-quality binding data. Of these parameters, minimizing non-specific binding (NSB) is one of the most imperative as it can directly affect the accuracy of your kinetic data.
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DKSH Helps Deliver Better Water Services in the Philippines
Product quality and compliance are essential to today’s modern water treatment facility. Many water treatment facilities are trying to leverage new technologies to respond quickly and efficiently to maintain stable water quality while reducing water treatment costs.
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Using the Right Physicochemical Characterization Tools to Keep the New Variants of SARS-CoV-2 Coronavirus at Bay
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a global health concern. At the time of writing, the number of diagnosed cases around the world has exceeded 194 million with Asia recording over 60.5 million.
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New Bioavailability and Bioequivalence Lab Leads the Way in the Philippines
By setting up a new bioavailability and bioequivalence laboratory, a leading testing and research lab was able to deliver better services to the under served generic pharmaceutical industries in the Philippines.
