Encapsulating a million single cells in individual scaffolds in agarose? Dolomite Bio’s nadAROSE kit can do it! It is a simple, low-cost, commercial solution for encapsulating up to a million single cells in individual micro-scaffolds in a high-throughput, reproducible manner.
Personalized cancer diagnostics tests, known as molecular diagnostics, are genetic tests that can be performed to determine whether patients have an inherited or acquired gene mutation associated with cancer. Cancer is one of the most common forms of disease caused by gene mutations.
As a leading microbiology laboratory in Thailand continues to add more tests to its already impressive range of services, DKSH was on hand with an advanced autoclave solution to help them better manage the waste and sterilization processes.
The International Laboratory, Analytical Equipment, and Biotechnology Exhibition (Korea Lab 2022), held recently at the KINTEX Exhibition in Ilsan, South Korea, provided DKSH with the opportunity to showcase some of the leading COVID-19 solutions, PCR equipment, and consumable products and services available for the Korean market.
Le Thanh Dat, Engineer, Technical Sales, DKSH
Monoclonal antibodies (mAbs) remain one of the fast-growing classes of biopharmaceuticals and are significantly improving the quality of life for patients all around the world. For greater understanding of bioprocess product quality attributes, subunit analysis is quick, simple, and automatable. Here’s a full workflow for automated sample preparation and LCMS analysis of mAbs obtained directly from complex bioreactor samples.
Existing tools for measuring and monitoring the structure of biotherapeutic molecules during formulation have had until now very significant limitations in sensitivity and have been very difficult to use. In this webinar, Amgen shares data that demonstrates the power of Microfluidic Modulation Spectroscopy (MMS), a novel, fully-automated IR technology, to generate high-quality, reproducible secondary structure data for protein therapeutics, including monoclonal antibodies.
G-protein-coupled receptors (GPCRs) represent a ubiquitous membrane protein family and are important drug targets. Their diverse signaling pathways are driven by complex pharmacology arising from a conformational ensemble rarely captured by structural methods.
Understanding the signaling pathways that biomarkers can activate can aid in the development of checkpoint immunotherapies. Surface Plasmon Resonance (SPR) is a common technique used to identify and elucidate biomarker interactions, signaling pathways, mechanisms of interaction, drug discovery, and the development of therapeutics. It provides a label-free, real-time method for determining binding kinetics and binding affinity of key biomolecular interactions. Systems like Alto from Nicoya Lifesciences, the world’s first digital SPR instrument to integrate digital microfluidics and nanotechnology, can measure biomolecules in pM concentrations in various sample matrices with high specificity while offering the versatility of working with a range of biomolecule types.
Pressure-Induced Protein Aggregation Detection: Protein aggregation is a recognized signal of instability and can lead to the loss of protein function. It is therefore crucial to detect protein aggregation early in the drug development process to inform further drug development decisions. Pressure, a stressor used for generating aggregates by impacting noncovalent interactions without the need to change temperature or solvents1, was employed to create aggregated protein for this spiked study.
Delivering Growth – in Asia and Beyond.
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