Surface Plasmon Resonance Sensors: A Comprehensive Guide for Scientists
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Surface Plasmon Resonance Sensors: A Comprehensive Guide for Scientists

SPR is a label-free technique that enables you to get in depth information on how two biomolecules are interacting. This is done on a sensor inside of an instrument such as the OpenSPR or Alto. SPR instruments are primarily used to measure binding affinity and kinetics, and are becoming increasingly more affordable and accessible as researchers realize the value that SPR data can bring to their research.

Ask an Expert: Efficient Development of Gene Therapy and Vaccines Through Comprehensive Viral Vector Characterization
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Ask an Expert: Efficient Development of Gene Therapy and Vaccines Through Comprehensive Viral Vector Characterization

Ever-more structurally complex bio-molecules and biological entities are coming into focus within the pharma development space, with fit-for-purpose analytics becoming more important to their success. Reducing development time and optimising formulation through applying orthogonal analytical technologies is key to bringing them to market in an efficient, risk-free manner. Date recorded: June 22, 2021 In addition…

Synthesis and Characterization of Antibody Drug Conjugates
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Synthesis and Characterization of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are attracting a tremendous amount of attention because they have the potential to revolutionize cancer treatment. Chemical ligation of cytotoxic agents to monoclonal antibodies allows the selective delivery of cytotoxins to tumor cells thereby potentially mitigating some of the damaging side-effects of cancer chemotherapy. There are currently nine FDA-approved ADCs and…

Insights Into Multi Fluorescence NTA Based EV Characterization – ISEV ‘EV Imaging in Vivo’ Workshop
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Insights Into Multi Fluorescence NTA Based EV Characterization – ISEV ‘EV Imaging in Vivo’ Workshop

Nanoparticle Tracking Analysis (NTA) with the Particle Metrix ZetaView® instrument family allows fast and reliable measurement of size, concentration, and Zeta Potential of nanoparticles. In contrast to scatter-based particle detection, fluorescence detection capability of the ZetaView® instrument allows the user to get biochemical information about particles. This increases the resolution and discriminatory power of the data. Furthermore,…

The pH Value Is a Key Factor in Cell and Tissue Cultures
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The pH Value Is a Key Factor in Cell and Tissue Cultures

The term ‘pH’ is derived from either ‘pondus hydrogenii’ or ‘potentia hydrogenii.’ Both are originally Latin phrases, with ‘pondus hydrogenii’ meaning ‘weight of hydrogen’ and ‘potentia hydrogenii’ meaning ‘power of hydrogen.’ The pH value is a non-dimensional number that measures how acidic or alkaline an aqueous solution is. It is defined as the negative decimal logarithm of the concentration of hydrogen ions. The strength of the acid or alkali is identified by color indicators.