Synthesis and Characterization of Antibody Drug Conjugates
Antibody drug conjugates (ADCs) are attracting a tremendous amount of attention because they have the potential to revolutionize cancer treatment. Chemical ligation of cytotoxic agents to monoclonal antibodies allows the selective delivery of cytotoxins to tumor cells thereby potentially mitigating some of the damaging side-effects of cancer chemotherapy. There are currently nine FDA-approved ADCs and…
