Target Selectivity of Multispecific Antibodies: Practical Analysis of Binding Kinetics and Avidity
Bispecific antibodies are promising therapeutics for targeting cancer cells with high specificity.
Insights Into Multi Fluorescence NTA Based EV Characterization – ISEV ‘EV Imaging in Vivo’ Workshop
Nanoparticle Tracking Analysis (NTA) with the Particle Metrix ZetaView® instrument family allows fast and reliable measurement of size, concentration, and Zeta Potential of nanoparticles. In contrast to scatter-based particle detection, fluorescence detection capability of the ZetaView® instrument allows the user to get biochemical information about particles. This increases the resolution and discriminatory power of the data. Furthermore,…
4 Ways To Reduce Non-specific Binding in Surface Plasmon Resonance Experiments
During an SPR experiment, there are many experimental parameters that must be controlled in order to optimize the performance of the system and to generate high-quality binding data. Of these parameters, minimizing non-specific binding (NSB) is one of the most imperative as it can directly affect the accuracy of your kinetic data.
Using the Right Physicochemical Characterization Tools to Keep the New Variants of SARS-CoV-2 Coronavirus at Bay
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a global health concern. At the time of writing, the number of diagnosed cases around the world has exceeded 194 million with Asia recording over 60.5 million.
Master Lipid Nanoparticle & Liposome Characterization with Light Scattering
Recent breakthroughs with mRNA-based vaccines highlight the potential of lipid-based particles as powerful and versatile delivery vectors for vaccines and gene therapies. Used to measure particle size, stability, zeta potential and particle concentration, light scattering techniques are used extensively in the characterization of lipid nanoparticle and liposome research.
Ask an Expert: Quantifying rAAV and Other Viral Vector Quality Attributes with Multi-angle DLS and Nanoparticle Tracking Analysis
Quick, label-free methods with minimal sample prep for simultaneously measuring rAAV aggregation, capsid charge, and particle concentration.
Bispecific Antibodies and Antibody Drug Conjugates: More Complex and Targeted Biologic Therapeutics
With the maturation of monoclonal antibodies (mAbs) based cancer immunotherapy drugs that target specific, actionable biomarkers, the biopharmaceutical industry has been developing more complex mAbs, such as bispecific antibodies and antibody drug conjugates. The Business Research Company projects the global monoclonal antibody market will exceed USD 170 billion by 2025 at a 12.9 percent CAGR. And in Asia, several companies are leading the way with these advanced antibody drug pipelines, including Astellas and Daiichi Sankyo in Japan, Adpro in Korea, and Miracogen in China.
Understanding Asia’s Growing Role in Epidermal Growth Factor Receptor (EGFR) Research
Lung cancer is one of the most common malignancies in the world, accounting for more than 1.6 million cases annually or twelve percent of all newly diagnosed cancers. It is also the leading cause of cancer deaths worldwide.
Lauda Hydro Water Bath Delivers Increased Efficiency for Leading R&D Laboratory in Singapore
A leading research and development center for analytical and biological sciences in Singapore gains added flexibility and increased efficiency with Lauda’s latest hydro water bath solutions.
Five Emerging Trends That Will Transform the Technology Sector Post-COVID-19
As disease outbreaks, epidemics and pandemics will likely become more common across the globe due to globalization, urbanization and climate change, the demand for innovations related to infectious disease control and virus outbreaks will continue to grow.
