Moving from 2D to 3D – Advanced Tools from Ibidi
Cell culture assays with two-dimensional monolayers have been a well-established and convenient tool for investigating cell behavior and function in many areas of cell biology, such as cancer biology and stem cell research. However, these 2D assays come with certain limitations, since they do not accurately reflect the in vivo cell-to-cell interactions. Because of these limitations, 3D cell culture models have gained more and more relevance, as they have been proven to yield more accurate insights and data about cell function, structure, and morphology.